Endometriosis ~ Abdominal Pain ~ Endo ~ Scar Tissue ~ Adhesions ~ Infertility ~ Hysterectomy

Monday, October 28, 2013

The Role of DJ-1 in the Pathogenesis of Endometriosis

Some light reading...

PLoS One. 2011; 6(3): e18074.
Published online 2011 March 21. doi:  10.1371/journal.pone.0018074
PMCID: PMC3061880

The Role of DJ-1 in the Pathogenesis of Endometriosis

Jean-Marc Vanacker, Editor



Endometriosis is an estrogen-dependent disease causing pelvic pain and infertility in 10% of reproductive-aged women. Despite a long history of the disease the pathogenesis of endometriosis is poorly understood. It is known that the expression of several proteins is either up or down regulated during endometriosis, but their precise role remains to be determined. DJ-1 is one such protein that is upregulated in eutopic endometrium of women having endometriosis suggesting that DJ-1 may be involved in the pathogenesis of endometriosis

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