Endometriosis ~ Abdominal Pain ~ Endo ~ Scar Tissue ~ Adhesions ~ Infertility ~ Hysterectomy
Showing posts with label birth control. Show all posts
Showing posts with label birth control. Show all posts

Friday, May 02, 2014

First Harry Reich Award presented at EFA’s Blossom Ball

First Harry Reich Award presented at EFA’s Blossom Ball 
8 MARCH 2014
Professors Linda Giudice and Liselotte Mettler were honoured at EFA’s 6th Annual Blossom Ball with the inaugural Harry Reich Award.

Yesterday evening, the Endometriosis Foundation of America (EFA) awarded the inaugural Harry Reich Award to recognise two extraordinary healthcare professionals, Professors Linda Giudice and Liselotte Mettler, for the difference these two women have made in the lives of other women through their practice, research, and advocacy.

Tamer Seckin presenting Linda Giudice with her Award at the Blossom Ball
In announcing these two awards, co-founder of EFA, Dr Tamer Seckin, emphasised how the achievements of both Linda Giudice and Liselotte Mettler are an inspiration and encouragement for women (with and without endometriosis) to take charge of their health!
Professor Giudice is a biochemist, gynaecologist, and reproductive endocrinologist with a specific clinical interest in endometriosisinfertilityassisted reproduction, and implantation and ovulatory disorders.
Her research focuses on environmental impacts on reproductive health, steroid hormone signalling in human endometrium, endometrial-placental interactions, endometrium as a mucosal tissue, and translational applications of human embryonic and endometrial stem cells.  She is distinguished professor and chair of the Department of Reproductive Sciences at the University of California San Francisco, immediate past-president of the ASRM, president-elect of the World Endometriosis Society, vice-president of the World Endometriosis Research Foundation, and a member of the Institute of Medicine of the National Academy of Sciences.
Tamer Seckin presenting Liselotte Mettler with her Award at the Blossom Ball
Professor Emeritus Mettler has specialised in reproductive medicine, gynaecological endoscopy, endometriosis, and gynaecological endocrinology since 1981 when she became deputy director of the Department of Obstetrics and Gynaecology at the University of Kiel.  Following her retirement she remains an honorary patron of the Kiel School of Gynaecological Endoscopy and Reproductive Medicine, where she still teaches up to a dozen international training courses each year.
She is also visiting professor to the German Medical Center and the Dubai Healthcare City.  Professor Mettler is a former board member and current ambassador of the World Endometriosis Society, a board member of the German Foundation for Endometriosis Research (SEF), and the General Secretary of the International Academy of Human Reproduction.

The Harry Reich Award

The Harry Reich Award is awarded by EFA to recognise extraordinary healthcare professionals, who are making a difference in women’s lives (and their families) by their practice, research, and advocacy.

Harry Reich with honouree Linda Giudice at the Blossom Ball
The award is named for Dr Harry Reich, a pioneer in the field of laparoscopic surgery, who performed many “firsts”, including: the first laparoscopic hysterectomy, the first pelvic lymphadenectomy for cancer, and the first excision of cul-de-sac endometriosis that included rectal resection.
Dr Reich, who has operated in more than 60 countries, is an honorary professor in Russia and Romania, as well as a Fellow (ad eundem) of the Royal College of Obstetricians and Gynaecologists in the UK for his pioneering work in the field of endoscopy.  Though retired, Dr Reich remains actively involved in many medical organisations and serves as a reviewer for multiple scientific journals.
Please visit Endometriosis.org for more news about endo.

Saturday, March 08, 2014

New Theory On Cause Of Endometriosis

New Theory On Cause Of Endometriosis
By News Staff | March 7th 2014 03:41 PM | Print | E-mail | Track Comments
   
Changes to two previously unstudied genes are the centerpiece of a new theory regarding the cause and development of endometriosis, a chronic and painful disease affecting 1 in 10 women.
The discovery by Northwestern Medicine scientists suggests epigenetic modification, a process that enhances or disrupts how DNA is read, is an integral component of the disease and its progression. Matthew Dyson, research assistant professor of obstetrics and gynecology at Northwestern University Feinberg School of Medicine and and Serdar Bulun, MD, chair of obstetrics and gynecology at Feinberg and Northwestern Memorial Hospital, also identified a novel role for a family of key gene regulators in the uterus.
"Until now, the scientific community was looking for a genetic mutation to explain endometriosis," said Bulun, a member of the Center for Genetic Medicine and the Robert H. Lurie Comprehensive Cancer Center of Northwestern University. "This is the first conclusive demonstration that the disease develops as a result of alterations in the epigenetic landscape and not from classical genetic mutations."
The findings were recently published in PLoS Genetics.
Women develop endometriosis when cells from the lining of the uterus, usually shed during menstruation, grow in other areas of the body. The persistent survival of these cells results in chronic pelvic pain and infertility. Although the cause of the disease has remained unknown on a cellular level, there have been several different models established to explain its development.
Endometriosis only occurs in menstruating primates, suggesting that the unique evolution behind uterine development and menstruation are linked to the disease. Scientists consider retrograde menstruation – cells moving up the fallopian tubes and into the pelvis – as one probable cause. Previous models, however, have been unable to explain why only 10 percent of women develop the disease when most experience retrograde menstruation at some point. Nor do they explain instances of endometriosis that arise independent of menstruation.
Bulun and Dyson propose that an epigenetic switch permits the expression of the genetic receptor GATA6 rather than GATA2, resulting in progesterone resistance and disease development.
"We believe an overwhelming number of these altered cells reach the lining of the abdominal cavity, survive and grow," Bulun said. "These findings could someday lead to the first noninvasive test for endometriosis."
Clinicians could then prevent the disease by placing teenagers predisposed to this epigenetic change on a birth control pill regimen, preventing the possibility of retrograde menstruation in the first place, Bulun said.
Dyson will also look to use the epigenetic fingerprint resulting from the presence of GATA6 rather than GATA2 as a potential diagnostic tool, since these epigenetic differences are readily detectable.
"These findings have the potential to shift how we view and treat the disease moving forward," Bulun said.


http://www.science20.com/news_articles/new_theory_cause_endometriosis-131257

Saturday, September 06, 2008

Find Out about ARD, before you have any surgery!

September is Adhesion Related Disorder Awareness Month.

What are Adhesions?
An ADHESION is a type of scar that forms an abnormal connection between two parts of the body. Adhesions can cause severe clinical problems. For example, adhesions involving the female reproductive organs (ovaries, Fallopian tubes) can and do cause infertility, dyspareunia (painful intercourse) and debilitating pelvic pain. Adhesions involving the bowel can cause bowel obstruction or blockage. Adhesions may form elsewhere such as around the heart, spine and in the hand where they lead to other problems.
Adhesions occur in response to injury of various kinds. For example, non-surgical insults such as endometriosis, infection, chemotherapy, radiation and cancer may damage tissue and initiate ADHESIONS. By far the most common kind of ADHESION is the one that forms after surgery. ADHESIONS typically occur at the site of a surgical procedure although they may also occur elsewhere.

Please visit these site for advocacy news and general education.
International Adhesion Society
Education helps prevent Adhesions!

Wednesday, August 27, 2008

Everything you always wanted to know about menopause but were afraid (or forgot) to ask

This article features a broad array of information.
Included as issues are bone density to heavy bleeding, even how it effects your teeth.

Also included:
Signs and symptoms of perimenopause
Signs that you are in perimenopause include:
Irregular menstrual periods.
Less frequent, light menstrual periods.
Heavier menstrual periods than you are used to having.

Symptoms of menopause
Symptoms related to menopause are caused by changing or dropping hormone levels and usually end 1 or 2 years after menopause. Some women continue to have symptoms for 5 or more years afterward. Menopause symptoms include:
Hot flashes.
Sleep disturbances (insomnia).
Emotional changes, such as mood swings or irritability.
A change in sexual interest or response.
Problems with concentration and memory that are linked to sleep loss and fluctuating hormones (not a permanent sign of aging).5
Headaches.
Rapid, irregular heartbeats (heart palpitations).
Generalized itching.
Menopause caused by surgery, chemotherapy, or radiation therapy can cause more severe symptoms than usual.6 Preexisting conditions such as depression, anxiety, sleep problems, or irritability can get worse during the perimenopausal transition.

When to Call a Doctor
During perimenopause or postmenopause, call your health professional about:
Menstrual periods that are unusually heavy, irregular, or prolonged (1½ to 2 times longer than normal).
Bleeding between menstrual periods, when periods have been regular.
Renewed bleeding after having no periods for 6 months or more.
Unexplained bleeding while you are taking hormones.
Perimenopause symptoms, such as insomnia, hot flashes, or mood swings, that aren't responding to home treatment and are interfering with your sleep or daily life.
Vaginal pain or dryness that does not improve with home treatment, or you have signs of a urinary tract infection.
If you have concerns about osteoporosis risk and prevention, talk to your health professional during your next office visit.
For more information, see the topics Abnormal Vaginal Bleeding, Dysfunctional Uterine Bleeding, and Osteoporosis.

Click here for even more!

Monday, February 25, 2008

Repros’ IND for the Commencement of Phase III Studies of Proellex ...

Repros’ IND for the Commencement of Phase III Studies of Proellex ...Business Wire (press release), CA - Feb 22, 2008Our lead drug, Proellex®, is a selective blocker of the progesterone receptor and is targeted for the treatment of uterine fibroids, endometriosis and ...RPRX

Thursday, January 31, 2008

Surgical outcome and long-term follow up after laparoscopic rectosigmoid resection in women with deep infiltrating endometriosis.

Seracchioli R, Poggioli G, Pierangeli F, Manuzzi L, Gualerzi B, Savelli L, Remorgida V, Mabrouk M, Venturoli S.
Center of Reconstructive Pelvic Endo-surgery, Reproductive Medicine Unit, S.Orsola Hospital, University of Bologna, Bologna, Italy. seracchioli@orsola-malpighi.med.unibo.it
The aim of this study was to assess the long-term outcome of treating severely symptomatic women with deep infiltrating intestinal endometriosis by laparoscopic segmental rectosigmoid resection. Detailed intraoperative and postoperative records and questionnaires (preoperatively, 1 month postoperatively and every 6 months for 3 years) were collected from 22 women. The estimated blood loss during surgery was 290 +/- 162 ml (range 180-600), and average hospital stay was 8 days (range 6-19). One woman required blood transfusion after surgery. Two cases were converted to laparotomy. One woman had early dehiscence of the anastomosis. Six months after surgery, there was a significant reduction of symptom scores (greater than 50% for most types of pain) related to intestinal localisation of endometriosis (P < 0.05). Score improvements were maintained during the whole period of follow up. Noncyclic pelvic pain scores showed significant reductions (P < 0.05) after 6 and 12 months, but there was a high recurrence rate later. Dysmenorrhoea and dyspareunia improved in 18/21 and 14/18 women with preoperative symptoms, respectively. Constipation, diarrhoea and rectal bleeding improved in all affected women for the whole period of follow up. Laparoscopic segmental rectosigmoid resection seems safe and effective in women with deep infiltrating colorectal endometriosis resulting in significant reductions in painful and dysfunctional symptoms associated with deep bowel involvement.
PMID: 17501958 [PubMed - indexed for MEDLINE]

Monday, January 28, 2008

Dyspareunia

From Wikipedia, the free encyclopedia:
Dyspareunia is painful sexual intercourse, due to medical or psychological causes. The term is used almost exclusively in women, although the problem can also occur in men. The causes are often reversible, even when long-standing, but self-perpetuating pain is a factor after the original cause has been removed.
Dyspareunia is considered to be primarily a physical, rather than an emotional, problem until proven otherwise. In most instances of dyspareunia, there is an original physical cause. Extreme forms, in which the woman's pelvic floor musculature contracts involuntarily, is termed vaginismus.
According to DSM-IV (American Psychiatric Association 1994), the diagnosis of dyspareunia is made when the patient complains of recurrent or persistent genital pain before, during, or after sexual intercourse that is not caused exclusively by lack of lubrication or by vaginismus. Clinically, it is often difficult to separate dyspareunia from vaginismus, since vaginismus may occur secondary to a history of dyspareunia and even mild vaginismus is often accompanied by dyspareunia. It is important to establish whether the dyspareunia is acquired or lifelong and whether it is generalized (complete) or situational. Further inquiry should determine whether the pain is superficial or deep - whether it occurs primarily at the vaginal outlet or vaginal barrel or upon deep thrusting against the cervix. Even when the pain can be reproduced during a physical examination, the possible role of psychological factors in either causing or maintaining the pain must be acknowledged and dealt with in treatment.

Thursday, January 24, 2008

The unforgettable ovary

By Gerald W. Deas, M.D.
Ladies, do you remember the velvet voice of Nat King Cole singing that song, "Unforgettable?" It went something like this, "Unforgettable, that's what you are, unforgettable, when near or far," etc. I actually forget the rest of the lyrics. anyhow, I'm sure that your ovaries might have gone crazy while listening to the rest of that romantic song.
The ovaries are not just a nest of eggs, but they secrete hormones which control almost all of the life saving chemical reactions in the female body. The ovaries don't forget what the female body needs to survive. Once every 28 to 30 days, when an egg is released (ovulation), there is an increase in the body temperature. If a pregnancy is desired, that is the time for the sperm to make its move in fertilizing the egg. In other words, make love before the temperature rises rather than later. This whole process of fertilization was not really understood until 1995. Millions of unwanted pregnancies have taken place due to misinformation. Just like I said, the ovary is not just an organ to increase our worldly population. That pair of small prune shaped unforgettable organs is responsible for a whole lot of things that take place in a woman's body and should not be removed unnecessarily when a hysterectomy is performed.
Can you believe, in this day and time at least 300,000 to 600,000 hysterectomies are performed due to abnormal uterine bleeding, fibroids, endometriosis, uterine prolapse and cancer. Often, the patient is advised to have a complete hysterectomy which entails not only removal of the uterus but also of the ovaries, medically known as oopherectomy. This procedure is justified by the surgeon to prevent ovarian and breast cancer.

Read More

Sunday, December 30, 2007

S.B. 1555 and H.R. 2596, also called the Access to Birth Control Act

Well these folks must not be very good at their jobs if they do not dispense doctor prescribed medicine That Help People in Pain!

It's discriminatory to withhold services as a pharmacist to customers.
Is your excuse freedom of religion?

Get another job bucko as you have no idea the pain and sickness you cause by denying the medicines woman's doctors prescribe.

It seems rather discriminatory an action a person could perpetrate!

What if the woman is post hysterectomy but still needs certain medicine? Denied?

What if getting pregnant would cost a woman their life?
Denied?

Emergency contraception for victims of rape?

Would these pharmacists put their money where their mouth are and adopt an unwanted child? They care so much for life after all but I doubt this would be the case.

It seems totally hypocritical and anther way to suppress women and deny their needs under the guise of religious belief!

Catch 22 and women lose again....and why is it always seem to be male in these stories????.

Druggist's decision carries consequences for small town By The Associated Press 12.24.07
RAPID CITY, S.D. — Pharmacist John Lane believes he has a responsibility to serve humankind through his profession.
Lane, who converted to Catholicism 10 years ago, also believes the "humankind" he pledged to protect includes fertilized eggs that, because of oral contraceptives, are not able to implant in a woman's uterus and grow into a baby.
There's more to it than that. But faith is clearly a big reason that, come Jan. 1, Lane will no longer dispense birth-control pills to his customers in Powder River County, Mont.
That decision wouldn't have much effect if Lane worked in Rapid City or surrounding towns, where dozens of other pharmacists and pharmacies are available and willing to fill prescriptions for birth control. But in a town of 450 people, Lane's decision will force customers to either get oral contraceptives by mail order or drive 80 miles to the nearest pharmacy.
Women who meet low-income requirements will still be able to get birth-control pills through the public-health nurse.
Many people have been angered by Lane's decision, which he announced Oct. 25 in a full-page ad in the Powder River Examiner. Many others have commended him for it.
Some, including health-care providers, say they like Lane and respect his religious beliefs but are concerned about how those beliefs will affect patients.
"It's a service that is taken away from women in general," said Jaci Phillips, Powder River Public Health nurse. "That's what concerns me."
Contraceptives may be available by mail, but that isn't the point, she said.
"I feel it should be basic health care for anyone to get any kind of prescription that a doctor provides for them," she said. "I just don't know how fair it is to pick and choose."
She's quick to emphasize that she has nothing against Lane.
"John's a great person," she said. "But if we're in health care, we've got to serve people."
Physician assistant LeRoy Biesheuvel shares Phillips' concerns.
"I am sad that he's not going to dispense (birth-control pills) anymore," said Biesheuvel, who has cared for Broadus residents for more than 20 years. "I respect his beliefs, but I think it's going to cause a little hardship on a few people in the community. I would rather have them available."
Lane believes a little inconvenience shouldn't outweigh his ability to work and provide for his family — he and his wife, Amy, have six children ranging in age from 5 months to 9 years — while living out the convictions of his faith.
"There are options for people who live here," he said.
Biesheuvel, Phillips and others are working on ways to keep oral contraceptives readily available to local residents and others who live in the county of 1,800 people.
A moral dilemmaLane grew up in Eagle Butte and graduated from the University of Montana in 1996. He worked in Nevada before moving to Broadus in 1998.
Broadus residents were happy to see him. The local drug store closed in the mid-1990s. It was replaced by a new pharmacy in Larry's IGA, the town's only grocery store.
"We were without a pharmacist for a while, and it's really difficult to get a pharmacist to come into a small place like this," said Biesheuvel, who noted that Lane sometimes goes in late at night to fill emergency prescriptions.
But over time, Lane has grown more uncomfortable with dispensing birth-control pills. Like many Catholics and conservative Christians, he believes human life begins at conception. He said women using the pill can still ovulate occasionally, meaning sex can result in a fertilized egg.
Because the pill also prevents a fertilized egg from implanting in the uterus, a fertilized egg — in Lane's eyes, a human being — may then pass out of the woman's body unnoticed.
"In the pledge I took when I became a pharmacist, I said, 'I vow to devote my professional life to the services of all humankind through the profession of pharmacy,'" Lane stated in his newspaper ad. "I am now unable to conclude that humankind begins at any other point besides conception."
The decision to stop dispensing birth control didn't come easily. Lane sought spiritual guidance, asking the diocesan administrator, the Very Rev. Jay H. Peterson, if he should view his responsibility to a geographically isolated community and to patients' easy access to medication as his moral obligation.
"The simple answer came back as 'no,' " Lane wrote in a letter to the Montana Pharmacy Association in which he called for a state law protecting the religious freedom of medical providers. "People's convenience does not trump moral obligation, and furthermore, he went on to say that it was in my spiritual best interest to conform my professional practice to the precepts of the church."
Pope Benedict XVI himself weighed in Oct. 29, telling the 25th International Congress of Catholic Pharmacists that they needed to raise public awareness "in order that all human beings are protected from conception to natural death."
Lane agrees that public awareness is important. The issue is bigger than one religion, he said. "I think that anybody who would naturally think of themselves as pro-life should really consider that issue more deeply."
Now what?
Meanwhile, women in Powder River County who take birth-control pills are left to consider the issue of how to get their medication.
Lane said he announced the policy change in October so women would have time to find alternate sources. He offered to help transfer prescriptions and gave information on pharmacies that would mail prescriptions. He gave the phone number of the county health office's family-planning program.
He also provided the Web sites and phone numbers for three organizations that promote natural family planning.
In his ad, Lane also apologized for inconveniencing his customers. He acknowledged that not every woman takes oral contraceptives to prevent pregnancy. Birth-control pills are also prescribed to treat endometriosis, acne, pre-menstrual syndrome and other conditions.
"For this reason, I must doubly apologize to those whom I will no longer be able to serve by this decision," he wrote.
Still, he stands by the fact that oral contraceptives are readily available by mail with a prescription.
And as others point out, mail-order pharmacies are becoming more and more common.
"There are numerous health plans that require a mail-order pharmacy (for maintenance drugs)," Ron Huether, executive secretary of the South Dakota Board of Pharmacy, said. "Other people don't seem to mind that at all."
A political stance There is another reason Lane decided to stop dispensing birth-control pills.
Three states — California, Illinois and New Jersey — require pharmacists to fill prescriptions for oral contraceptives. Other states, including South Dakota, have "conscience clauses" that protect pharmacists who choose not to fill certain prescriptions.
Montana law doesn't address the issue. Lane expects state legislators to consider it, possibly during the next legislative session, partly because a Great Falls, Mont., pharmacy announced earlier this year that its pharmacists would no longer dispense oral contraceptives.
"I thought it would be important to have more voices on this issue," Lane said. "Otherwise, the one example is going to be written off as sort of a fluke and not taken seriously when they're considering this issue."
Lane fears that requiring pharmacists to dispense drugs that conflict with their moral or religious beliefs could lead to similar laws that would require doctors to perform abortions, vasectomies and other procedures.
A bill currently before the U.S. Congress — S.B. 1555 and H.R. 2596, also called the Access to Birth Control Act — would impose fines of up to $5,000 per day of violation for pharmacists who refuse to fill legal prescriptions for birth-control pills.
"I would hate for these things to get decided without there being a conservative voice on the issue," Lane said.
But others fear that allowing pharmacists to pick and choose which drugs they will dispense sets a dangerous precedent.
"Who decides what is next?" Jaci Phillips asks. If a person believes AIDS or other illness is a punishment from God, she asks, would they be allowed to withhold other medications?
"If they want to be serious about life in general, protecting life, then they probably have to think about every medication that goes out," Phillips said, noting that many types of drugs can have disastrous effects on a fertilized egg.
"I've often wondered if this affected men as greatly as women and young women, would there be any question whether this would be dispensed?" she asked. "(Women) have a right to decide what to do with their lives and their bodies."
Mixed reactionsSnyder Drug in Great Falls, Mont., is owned and operated by Stuart and Kyla Anderson and Kurt and Kori Depner, all pharmacists and all Catholic. Their announcement last June that their store would no longer sell oral contraceptives brought criticism from abortion-rights groups, including Planned Parenthood, and became a topic on numerous blogs.
Staff at the Great Falls Tribune said letters to the editor were divided, some in support and some opposed.
In Broadus, letters have also run about 50-50 for and against the policy change, said Joe Stuver, who serves as editor, publisher and ad manager for the Powder River Examiner.
"(John) is really a good guy, and that's what makes it hard," he said. "It wasn't something that came easy to him."
Phillips received a number of calls, nearly all of them from people angry about the news.
Lane says he has received far more compliments than complaints.
"I was expecting more of a backlash," he said.
Larry's IGA, the grocery store that houses the pharmacy, did get angry calls from customers saying they would no longer shop at the store. But they, too, received compliments. So far, sales haven't been affected, said store manager Mark Wenzel.
Still, some worry that if people drive 80 miles to the closest pharmacy, they might decide to buy their groceries and other goods there, too.
"I would have never before this encouraged people to go to mail-order pharmacists because I think we need to support our hometown pharmacist," Phillips said. "We need to keep those services local, and I just hate to lose anything that's local."
"This is a tough issue," Wenzel agreed. "It's one of the toughest things I've ever gone through."
Planning for the futureWith little time left before the pharmacy's new policy change takes effect, Wenzel, Larry's IGA owner Larry Woolston, Biesheuvel, Phillips, Lane and others are exploring other ways to continue providing oral contraceptives locally.
One idea is to bring in a pharmacist once or twice a month who would fill birth-control prescriptions. Another is to get permission from the Montana State Board of Pharmacy for Biesheuvel to dispense oral contraceptives from Powder River Medical Clinic, where he works.
"It's illegal for me to dispense prescriptions from the clinic because there's an operating pharmacy within five miles," Biesheuvel explained. "But if this drug is not available through the local pharmacy, if we can get permission from the state, that might be a possibility."
In terms of the future, state legislators are almost certain to discuss the issue at some point. Those who believe pharmacists should be able to decide whether to dispense birth control and those who believe they should be required to do so say they want legislators to come up with a clear policy on the matter.
And while health-care providers in isolated areas would like to ensure that women have ready access to oral contraceptives, they also realize what could hang in the balance.
As Lane noted in his letter to the Montana Pharmacy Association, if the state adopts laws that override a medical provider's "moral conscience," ''then some places, like Broadus, may no longer have pharmacy service at all."
That's a scenario no one wants, those involved with the issue say.