Lupron Depot (leuprolide acetate for depot suspension) is a GnRH agonist -- a hormone that works in two distinct phases. Phase one stimulates the ovaries causing them to produce more of the most potent of the three estrogens produced by women -- estradiol. In phase two the messenger hormones that tell the ovaries to produce estrogen decline dramatically. This causes a significant reduction in estrogen levels, and causes women to experience menopause-like side effects.
The most common use for Lupron in women is for the treatment of endometriosis. Lupron is also sometimes used in women for the treatment of uterine fibroid tumors. In men, Lupron is used to treat advanced prostate cancer, and the drug is used in children who are diagnosed with central precocious puberty (early puberty).
Deciding whether to use Lupron should include knowing all the facts about the benefits and side effects and making an informed choice.